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Brian Mengel,
Civil Servant
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The efficacy data obtained for Lupron Depot was based on these studies, and the researchers found that Lupron Depot is effective for the management of endometriosis, including pain relief and reduction of endometriotic lesions.
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Albert Graham,
Backyard Pool Drainer
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In the women in whom surgeons could actually see endometriotic lesions and implants, the surgeons observed that a full course of Lupron Depot therapy had substantially reduced the size of the endometrial implants.
In clinical studies, women with pelvic pain underwent diagnostic laparoscopy surgery before and after they were treated with Lupron Depot for 6 months.
Was it because just 6 months (not 1 year or 5 years) after stopping Lupron Depot, 80% of women with painful menstruations (dysmenorrhea) had symptoms again - they were not symptom-free.
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Zhang Xian Qian,
Ex-Olympic Swimmer
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Lupron Depot (leuprolide acetate for depot suspension) in the treatment of endometriosis: a randomized, placebo-controlled, double-blind study.
Dlugi AM, Miller JD, Knittle J, Lupron Study Group, Lupron depot (leuprolide acetate for depot suspension) in the treatment of endometriosis: a randomized, placebo-controlled, double-blind study.
No placebo-controlled studies were done prior to the FDA approval of Lupron Depot.
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Todd Porter,
Gym Attendent
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Over half of women with pelvic pain (dysmenorrhea) were symptom-free a year after Lupron Depot therapy.
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Adam Findley,
Professional Motivator
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Lupron Depot therapy had to achieve success in these areas greater than placebo in order to be approved by the FDA.
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Billie Kirgan,
Machinist
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Leuprolide acetate [Lupron Depot] has been used to decrease uterine size and shrink leiomyomata [uterine fibroids]
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Arthur Dawkins,
Astro-physicist
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Rutgers stated that with Lupron Depot for 3 months "the mean external arterial diameter in the myomas of the GnRH-a-treated patients was 24% smaller than those in the placebo subjects.
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Josh Hogan,
Commander
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TAP states that "The approval of Lupron Depot for endometriosis was based on two clinical trials involving close to 400 women with endometriosis who were treated either with Lupron Depot, danazol, or a placebo.
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